Structure of PDB 4ire Chain D

Receptor sequence
>4ireD (length=313) Species: 251221 (Gloeobacter violaceus PCC 7421) [Search protein sequence]
MVSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLA
FDPVRSGVRVKTYEPEAIWIPEIRFVNVENARDADVVNISVSPDGTVQYL
ERFSARVLSPLDFRRYPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKND
DVFLTGWDIESFTAVVKPANFALQNRLESKLDYQLRISRQYFSYIPNIIL
PMLFILFISWTAFWSTSYEANVTLVVSTLIAHIAFNILVETNLPKTPYMT
YTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAASITRASRIAFPVVF
LLANIILAFLFFG
3D structure
PDB4ire Signal transduction pathways in the pentameric ligand-gated ion channels.
ChainD
Resolution3.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OXL D R77 F78 A84 R85 R74 F75 A81 R82
BS02 OXL D T219 Y221 H277 K280 T216 Y218 H274 K277
BS03 OXL D D86 D88 R105 S107 D83 D85 R102 S104
BS04 OXL D V90 N91 I92 V87 N88 I89
BS05 LMD D A237 N245 A234 N242
BS06 OXL D R293 R296 R290 R293
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4ire, PDBe:4ire, PDBj:4ire
PDBsum4ire
PubMed23667707
UniProtQ7NDN8|GLIC_GLOVI Proton-gated ion channel (Gene Name=glvI)

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