Structure of PDB 4ien Chain D

Receptor sequence
>4ienD (length=154) Species: 272831 (Neisseria meningitidis FAM18) [Search protein sequence]
RQLPSHELIMSELMMPDTANFSGNVHGGELLLLLDQVAYSCASRYSGNYC
VTLSVDKVLFKEPIHIGDLVTFYAAVNYTGRTSMEIGIRVEAQNIRTGEI
RHTNSCYFTMVAVKDGKPVPVPPLEILTDRQRCRYEKAKKRRDISLQASE
DMSC
3D structure
PDB4ien Expression, purification and crystallization of acetyl-CoA hydrolase from Neisseria meningitidis.
ChainD
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.2.20: acyl-CoA hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA D G31 L34 F64 K65 E66 P67 G27 L30 F60 K61 E62 P63
BS02 GDP D D155 S157 C158 D151 S153 C154
BS03 COA D V55 T56 L57 R85 T86 S87 R146 S149 L150 V51 T52 L53 R81 T82 S83 R142 S145 L146
BS04 GDP D Y77 A78 A79 N81 G91 I92 R93 S109 Y111 R138 Y73 A74 A75 N77 G87 I88 R89 S105 Y107 R134
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016790 thiolester hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4ien, PDBe:4ien, PDBj:4ien
PDBsum4ien
PubMed24192375
UniProtA1KUS8

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