Structure of PDB 4gxg Chain D

Receptor sequence
>4gxgD (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]
LAEHLLKPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGNI
TKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLRF
IQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAALY
AAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDVIYEMYTQMNA
ELNYKV
3D structure
PDB4gxg Structural insights into lipid-dependent reversible dimerization of human GLTP.
ChainD
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EIS D F42 I45 D48 I49 N52 K55 A93 W96 F103 L136 H140 F148 Y207 F39 I42 D45 I46 N49 K52 A90 W93 F100 L133 H137 F145 Y204
BS02 EIS D V41 P44 I45 F148 V38 P41 I42 F145
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0017089 glycolipid transfer activity
GO:0042802 identical protein binding
GO:0051861 glycolipid binding
GO:0120013 lipid transfer activity
GO:1902387 ceramide 1-phosphate binding
GO:1902388 ceramide 1-phosphate transfer activity
Biological Process
GO:0006869 lipid transport
GO:0035627 ceramide transport
GO:0035902 response to immobilization stress
GO:0046836 glycolipid transport
GO:0120009 intermembrane lipid transfer
GO:1902389 ceramide 1-phosphate transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4gxg, PDBe:4gxg, PDBj:4gxg
PDBsum4gxg
PubMed23519669
UniProtQ9NZD2|GLTP_HUMAN Glycolipid transfer protein (Gene Name=GLTP)

[Back to BioLiP]