Structure of PDB 4grs Chain D

Receptor sequence
>4grsD (length=331) Species: 186497,243274 [Search protein sequence]
MIVVLKPGSTEEDIRKVVKLAESYNLKCHISKGQERTVIGIIGDDRYVVA
DKFESLDCVESVVRVLKPYKLVSREFHPEDTVIDLGDVKIGNGYFTIIAG
PCSIESRDQIMKVAEFLAEVGIKVLRGGAFKPRPYSFQGYGEKALRWMRE
AADEYGLVTVTEVMDTRHVELVAKYSDILQIGARNSQNFELLKEVGKVEN
PVLLKRGMGNTIQELLYSAEYIMAQGNENVILCERGIRTFETATRFTLDI
SAVPVVKELSHLPIIVDPSHPAGRRSLVIPLAKAAYAIGADGIMVEVHPE
PEKALSDSQQQLTFDDFLQLLKELEALGWKG
3D structure
PDB4grs Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR D S31 Q34 R36 V38 S31 Q34 R36 V38
BS02 TYR D M1 I41 I42 G43 V65 L66 M1 I41 I42 G43 V65 L66
Gene Ontology
Molecular Function
GO:0016832 aldehyde-lyase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4grs, PDBe:4grs, PDBj:4grs
PDBsum4grs
PubMed23345433
UniProtQ8U0A9;
Q9WYH8|AROF_THEMA Phospho-2-dehydro-3-deoxyheptonate aldolase (Gene Name=aroF)

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