Structure of PDB 4gi7 Chain D

Receptor sequence
>4gi7D (length=308) Species: 507522 (Klebsiella pneumoniae 342) [Search protein sequence]
MTPYLQFNRHQWAALRDSVPMTLTEDEITRLKGINEDLSLEEVAEIYLPL
SRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVL
QALLSRWPEHRHVELITTDGFLHPNSVLKERGLMKKKGFPQSYDMHRLVK
FVSDLKSGVPQATAPVYSHLIYDVIPDGDKTVAQPDILILEGLNVLQSGM
DYPHDPHHVFVSDFVDFSIYVDAPEELLKSWYINRFLKFREGAFTDPDSY
FHNYAKLSKEEAVDIATSLWNEINLMNLKENILPTRERASLIMTKSANHS
VNQVRLRK
3D structure
PDB4gi7 Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
ChainD
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.33: pantothenate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D N1043 D1045 A1098 G1100 K1101 S1102 T1103 R1243 H1307 N35 D37 A90 G92 K93 S94 T95 R235 H299
BS02 0JR D D1127 H1177 Y1180 Y1240 Y1258 F1259 Y1262 N1282 D119 H169 Y172 Y232 Y250 F251 Y254 N274
Gene Ontology
Molecular Function
GO:0004594 pantothenate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4gi7, PDBe:4gi7, PDBj:4gi7
PDBsum4gi7
PubMed23553820
UniProtB5XYG3|COAA_KLEP3 Pantothenate kinase (Gene Name=coaA)

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