Structure of PDB 4gbn Chain D
Receptor sequence
>4gbnD (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTDKT
3D structure
PDB
4gbn
A T3R3 hexamer of the human insulin variant B28Asp.
Chain
D
Resolution
1.872 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
D
G8 V12 E13 Y16 R22 G23 F24 F25 Y26 D28 K29
G8 V12 E13 Y16 R22 G23 F24 F25 Y26 D28 K29
BS02
peptide
D
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 D28 T30
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 D28 T30
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:4gbn
,
PDBe:4gbn
,
PDBj:4gbn
PDBsum
4gbn
PubMed
23428413
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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