Structure of PDB 4g8a Chain D

Receptor sequence
>4g8aD (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
QKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKGSKGLLHIFYIPR
RDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTIS
FSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPN
3D structure
PDB4g8a Structural analyses of human Toll-like receptor 4 polymorphisms D299G and T399I
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LP4 D F76 Y102 S118 F119 S120 F58 Y84 S100 F101 S102
BS02 LP5 D L87 R90 F121 K122 I124 F126 F151 L69 R72 F103 K104 I106 F108 F133
Gene Ontology
Molecular Function
GO:0001530 lipopolysaccharide binding
GO:0035662 Toll-like receptor 4 binding
Biological Process
GO:0045087 innate immune response

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Molecular Function
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Biological Process
External links
PDB RCSB:4g8a, PDBe:4g8a, PDBj:4g8a
PDBsum4g8a
PubMed23055527
UniProtQ9Y6Y9|LY96_HUMAN Lymphocyte antigen 96 (Gene Name=LY96)

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