Structure of PDB 4e80 Chain D

Receptor sequence
>4e80D (length=324) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
HKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFGS
LESGLALKNSDMDLCVLMDDTIALQFYEELIAEGFEGKFLQRARIPIIKL
TSSFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMVLLVKHWAKRKQINS
PYFGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSPLKQEKIVDGFDVGFD
DKLEDIPPSQNYSSLGSLLHGFFRFYAYKFEPREKVVTFRRPDGYLTKQE
KGWTSATEHTGSADKDRYILAIEDPFEISHNVGRTVSSSGLYRIRGEFMA
ASRLLNSRSYPIPYDSLFEEAPIP
3D structure
PDB4e80 Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase.
ChainD
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UTP D G89 S90 A168 N171 T172 K197 S211 Y212 G49 S50 A115 N118 T119 K144 S158 Y159
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0002134 UTP binding
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
GO:1990817 poly(A) RNA polymerase activity
Biological Process
GO:0036450 polyuridylation-dependent decapping of nuclear-transcribed mRNA
GO:0071076 RNA 3' uridylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4e80, PDBe:4e80, PDBj:4e80
PDBsum4e80
PubMed22751018
UniProtO13833|CID1_SCHPO Terminal uridylyltransferase cid1 (Gene Name=cid1)

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