Structure of PDB 4e5j Chain D

Receptor sequence
>4e5jD (length=179) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHTYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRGLWDSFRQSERAA
3D structure
PDB4e5j Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
ChainD
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 581 D H41 E80 D108 E119 K134 H41 E61 D89 E100 K115 MOAD: Ki=18.7uM
BS02 581 D K34 A37 H41 V122 R124 K34 A37 H41 V103 R105 MOAD: Ki=18.7uM
BS03 MN D H41 D108 E119 I120 H41 D89 E100 I101
BS04 MN D E80 D108 E61 D89
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:4e5j, PDBe:4e5j, PDBj:4e5j
PDBsum4e5j
PubMed22876176
UniProtQ5EP34

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