Structure of PDB 4e5i Chain D

Receptor sequence
>4e5iD (length=183) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHTYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRGLWDSFRQSERAAAELA
3D structure
PDB4e5i Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
ChainD
Resolution2.944 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN D H41 D108 E119 I120 H41 D89 E100 I101
BS02 MN D L106 P107 D108 L87 P88 D89
BS03 0N9 D H41 K134 K137 H41 K115 K118
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4e5i, PDBe:4e5i, PDBj:4e5i
PDBsum4e5i
PubMed22876176
UniProtQ5EP34

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