Structure of PDB 4e2s Chain D

Receptor sequence
>4e2sD (length=258) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
PIYWKATNPTLSPSHLQDLPGFTRSVYKRDHALITPESHVYSPLPDWTNT
LGAYLITPATGSHFVMYLAKMKEMSSSGLPPQDIERLIFVVEGAVTLTNS
SSKKLTVDSYAYLPPNFHHSLDCVESATLVVFERRYEYLGSHTTELIVGS
TDKQPLLETPGEVFELRKLLPMSVAYDFNIHTMDFQPGEFLNVKEVHYNQ
HGLLLLEGQGIYRLGDNWYPVQAGDVIWMAPFVPQWYAALGKTRSRYLLY
KDVNRNPL
3D structure
PDB4e2s Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana
ChainD
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.3.26: (S)-ureidoglycine aminohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D E235 H237 H241 Q275 E195 H197 H201 Q235
BS02 UGY D M223 E235 H241 Q275 Y287 M183 E195 H201 Q235 Y247
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0071522 ureidoglycine aminohydrolase activity
Biological Process
GO:0000256 allantoin catabolic process
GO:0006144 purine nucleobase metabolic process
GO:0006145 purine nucleobase catabolic process
GO:0006355 regulation of DNA-templated transcription
GO:0010136 ureide catabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4e2s, PDBe:4e2s, PDBj:4e2s
PDBsum4e2s
PubMed22493446
UniProtQ8GXV5|UGHY_ARATH (S)-ureidoglycine aminohydrolase (Gene Name=UGLYAH)

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