Structure of PDB 4dbm Chain D

Receptor sequence
>4dbmD (length=213) Species: 6500 (Aplysia californica) [Search protein sequence]
DYKDDDDKLHSQANLMRLKSDLFNMYPGPTKDDPLTVTLGFTLQDIVKAD
SSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYS
STRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKF
GSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEP
YIDVNLVVKFRER
3D structure
PDB4dbm Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0J0 D Y93 W147 Y188 C190 C191 Y195 Y99 W153 Y194 C196 C197 Y201 MOAD: Kd=24nM
BS02 0J0 D Y55 Q57 V108 M116 I118 Y61 Q63 V114 M122 I124 MOAD: Kd=24nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4dbm, PDBe:4dbm, PDBj:4dbm
PDBsum4dbm
PubMed22394239
UniProtQ8WSF8

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