Structure of PDB 4cr7 Chain D

Receptor sequence
>4cr7D (length=257) Species: 240 (Flavobacterium sp. 141-8) [Search protein sequence]
GRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDLAPRLAATRYEEPG
AIPIACDLDRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDAD
WDRYVDVNMTGTFLTCRAGARAMVAAGAGRSARIITIGSVNSFMAEPEAA
AYVAAKGGVAMLTRAMAVDLARHGILVNMIAPGPVDVTGNNTGYSEPRLA
EQVLDEVALGRPGLPEEVATAAVFLAEDGSSFITGSTITIDGGLSAMIFG
GMREGRR
3D structure
PDB4cr7 Crystal Structures and Functional Studies Clarify Substrate Selectivity and Catalytic Residues for the Unique Orphan Enzyme N-Acetyl-D-Mannosamine Dehydrogenase.
ChainD
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G26 S153 Y166 K170
Catalytic site (residue number reindexed from 1) G16 S139 Y152 K156
Enzyme Commision number 1.1.1.233: N-acylmannosamine 1-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN D M158 E220 L258 S259 M261 I262 M144 E206 L244 S245 M247 I248
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0050123 N-acylmannosamine 1-dehydrogenase activity

View graph for
Molecular Function
External links
PDB RCSB:4cr7, PDBe:4cr7, PDBj:4cr7
PDBsum4cr7
PubMed24969681
UniProtP22441|DHMA_FLAS1 N-acylmannosamine 1-dehydrogenase

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