Structure of PDB 4co9 Chain D

Receptor sequence
>4co9D (length=206) Species: 198094 (Bacillus anthracis str. Ames) [Search protein sequence]
SKWIDISQPLNNDIATWPGDTPFSYEVLWSKEESGSVNVGKLTMSIHTGT
HIDAPFHFDNDGKKVLDLDIQVYVGPTRIIDVSNLESIGKKELEKFHLEG
VERLLLRTSSHGKANEFPDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPL
DDKELAAHHQLFKHSIHILENVVLDHVADGDYELIALPLALSDADGSPVR
AVIRPI
3D structure
PDB4co9 Structure of Bacterial Kynurenine Formamidase Reveals a Crowded Binuclear-Zinc Catalytic Site Primed to Generate a Potent Nucleophile.
ChainD
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.9: arylformamidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D D56 H161 E173 D53 H158 E170
BS02 ZN D H50 H54 D56 E173 H47 H51 D53 E170
Gene Ontology
Molecular Function
GO:0004061 arylformamidase activity
GO:0004328 formamidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006569 tryptophan catabolic process
GO:0019441 tryptophan catabolic process to kynurenine
GO:0043420 anthranilate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4co9, PDBe:4co9, PDBj:4co9
PDBsum4co9
PubMed24942958
UniProtQ81PP9|KYNB_BACAN Kynurenine formamidase (Gene Name=kynB)

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