Structure of PDB 4c5l Chain D

Receptor sequence
>4c5lD (length=269) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
GALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALTAIVTMDKDTWS
HDVTPLPMDVFEKQLETALSIGPDAIKTGMLGTEEIIKRAGEVYEASNAQ
YFVVDPVMVCKGNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLGKLNSI
EDMKKAATIIFDKGAQHVIIKGGKALDQDKSYDLYYDGQTFYQLTTDMFQ
YNHGAGCTFAAATTAYLANGKSPKEAVISAKAFVASAIKNGWKMNDFVGP
VDHGAYNRIEHIDVEVTEV
3D structure
PDB4c5l A Subfamily of Bacterial Ribokinases Utilizes a Hemithioacetal for Pyridoxal Phosphate Salvage.
ChainD
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K176 N209 G211 A212 G213 C214
Catalytic site (residue number reindexed from 1) K171 N202 G204 A205 G206 C207
Enzyme Commision number 2.7.1.35: pyridoxal kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UEG D G11 S12 D13 G19 V42 C110 C214 G11 S12 D13 G19 V42 C110 C207
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008902 hydroxymethylpyrimidine kinase activity
GO:0008972 phosphomethylpyrimidine kinase activity
GO:0016301 kinase activity
Biological Process
GO:0009228 thiamine biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4c5l, PDBe:4c5l, PDBj:4c5l
PDBsum4c5l
PubMed24601602
UniProtA0A0H3JTP0

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