Structure of PDB 4c5k Chain D

Receptor sequence
>4c5kD (length=276) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
GALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALTAIVTMDKDTWS
HDVTPLPMDVFEKQLETALSIGPDAIKTGMLGTEEIIKRAGEVYEASNAQ
YFVVDPVMVCKGEDEVLNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLG
KLNSIEDMKKAATIIFDKGAQHVIIKGGKALDQDKSYDLYYDGQTFYQLT
TDMFQQSYNHGAGCTFAAATTAYLANGKSPKEAVISAKAFVASAIKNGWK
MNDFVGPVDHGAYNRIEHIDVEVTEV
3D structure
PDB4c5k A Subfamily of Bacterial Ribokinases Utilizes a Hemithioacetal for Pyridoxal Phosphate Salvage.
ChainD
Resolution1.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K176 N209 G211 A212 G213 C214
Catalytic site (residue number reindexed from 1) K176 N209 G211 A212 G213 C214
Enzyme Commision number 2.7.1.35: pyridoxal kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D K176 G178 K179 S186 D188 M203 F204 N209 I245 K176 G178 K179 S186 D188 M203 F204 N209 I245
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008902 hydroxymethylpyrimidine kinase activity
GO:0008972 phosphomethylpyrimidine kinase activity
GO:0016301 kinase activity
Biological Process
GO:0009228 thiamine biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4c5k, PDBe:4c5k, PDBj:4c5k
PDBsum4c5k
PubMed24601602
UniProtA0A0H3JTP0

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