Structure of PDB 4c2d Chain D

Receptor sequence
>4c2dD (length=343) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
SERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYM
DKQTAKQFSDSLDLETVFASEKKVQGHSVGYIAISTFSEHTAEDFAKALR
ELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPYIQIAERNGDKK
RYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGKG
TVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIKQPDYFSAGP
LQLKEPLKVDMNNEDVKHAQVLLKGLSFDPGREDGYFSKDMKKAVMAFQD
QNKLNKTGVIDTRTAETLNQQIEKKKSDEKNDLQLQTALKSLF
3D structure
PDB4c2d Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.102: C-terminal processing peptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D L257 Q338 Q339 L122 Q203 Q204
BS02 peptide D G254 G255 S309 A310 K334 K350 G119 G120 S174 A175 K199 K215
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0042277 peptide binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0007165 signal transduction
GO:0030435 sporulation resulting in formation of a cellular spore
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4c2d, PDBe:4c2d, PDBj:4c2d
PDBsum4c2d
PubMed24243021
UniProtO35002|CTPB_BACSU Carboxy-terminal processing protease CtpB (Gene Name=ctpB)

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