Structure of PDB 4bw5 Chain D

Receptor sequence
>4bw5D (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
KWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHV
CVSPQELETLIQHALDADNAGVSPISHWDLGSAFFFAGTVITTIGYGNIA
PSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKK
QVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTL
TTVGFGDFVAGGNYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK
3D structure
PDB4bw5 K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
ChainD
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K D G174 Y175 G176 G283 F284 G285 G95 Y96 G97 G204 F205 G206
BS02 K D I173 G174 Y175 V282 G283 F284 I94 G95 Y96 V203 G204 F205
BS03 K D T172 I173 G174 T281 V282 T93 I94 G95 T202 V203
BS04 K D T172 T281 T93 T202
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bw5, PDBe:4bw5, PDBj:4bw5
PDBsum4bw5
PubMed25766236
UniProtP57789|KCNKA_HUMAN Potassium channel subfamily K member 10 (Gene Name=KCNK10)

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