Structure of PDB 4bdm Chain D

Receptor sequence
>4bdmD (length=248) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIR
LVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSA
PFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKIST
YDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCN
LTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW
3D structure
PDB4bdm Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements.
ChainD
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KAI D Y488 P516 A518 R523 G688 A689 T690 E738 Y57 P85 A87 R92 G137 A138 T139 E187 BindingDB: Ki=12.7nM,Kd=39nM,EC50=1800nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4bdm, PDBe:4bdm, PDBj:4bdm
PDBsum4bdm
PubMed23720540
UniProtP42260|GRIK2_RAT Glutamate receptor ionotropic, kainate 2 (Gene Name=Grik2)

[Back to BioLiP]