Structure of PDB 4b98 Chain D

Receptor sequence
>4b98D (length=441) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
APPVSSELNLRAHWMPFSANRNFQKDPRIIVAAEGSWLTDDKGRKVYDSL
SGLWTCGAGHSRKEIQEAVARQLGTLDYSPGFQYGHPLSFQLAEKIAGLL
PGELNHVFFTGSGSECADTSIKMARAYWRLKGQPQKTKLIGRARGYHGVN
VAGTSLGGIGGNRKMFGQLMDVDHLPHTLQPGMAFTRGMAQTGGVELANE
LLKLIELHDASNIAAVIVEPMSGSAGVLVPPVGYLQRLREICDQHNILLI
FDEVITAFGRLGTYSGAEYFGVTPDLMNVAKQVTNGAVPMGAVIASSEIY
DTFMNQALPEHAVEFSHGYTYSAHPVACAAGLAALDILARDNLVQQSAEL
APHFEKGLHGLQGAKNVIDIRNCGLAGAIQIAPRDGDPTVRPFEAGMKLW
QQGFYVRFGGDTLQFGPTFNARPEELDRLFDAVGEALNGIA
3D structure
PDB4b98 Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
ChainD
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F24 Y153 E226 D259 I262 K288 Q421
Catalytic site (residue number reindexed from 1) F17 Y146 E219 D252 I255 K281 Q414
Enzyme Commision number 2.6.1.18: beta-alanine--pyruvate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PXG D Y326 T327 Y319 T320
BS02 PXG D W61 S119 G120 S121 Y153 H154 G155 S231 D259 V261 I262 K288 R414 Q421 W54 S112 G113 S114 Y146 H147 G148 S224 D252 V254 I255 K281 R407 Q414
BS03 PLP D G240 Q243 F277 G233 Q236 F270
Gene Ontology
Molecular Function
GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO:0008483 transaminase activity
GO:0016223 beta-alanine:pyruvate transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009102 biotin biosynthetic process
GO:0019483 beta-alanine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4b98, PDBe:4b98, PDBj:4b98
PDBsum4b98
PubMed23519665
UniProtQ9I700|BAUA_PSEAE Beta-alanine--pyruvate aminotransferase (Gene Name=bauA)

[Back to BioLiP]