Structure of PDB 4b7a Chain D

Receptor sequence

>4b7aD (length=670) Species: 85995 (Mycothermus thermophilus)

SPLAAYEVDDSTGYLTSDVGGPIQDQTSLKAGIRGPTLLEDFMFRQKIQH
FDHERVPERAVHARGAGAHGTFTSYADWSNITAASFLNATGKQTPVFVRF
STVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDAIQFPD
LIHSVKPRPDNEIPQAATAHDSAWDFFSQQPSTMHTLFWAMSGHGIPRSY
RHMDGFGVHTFRFVKDDGSSKLIKWHFKSRQGKASLVWEEAQVLSGKNAD
FHRQDLWDAIESGNGPEWDVCVQIVDESQAQAFGFDLLDPTKIIPEEYAP
LTKLGLLKLDRNPTNYFAETEQVMFQPGHIVRGIDFTEDPLLQGRLFSYL
DTQLNRNGGPNFEQLPINMPRVPIHNNNRDGAGQMFIHRNKYPYTPNTLN
SGYPRQANQNAGRGFFTAPGRTASGALVREVSPTFNDHWSQPRLFFNSLT
PVEQQFLVNAMRFEISLVKSEEVKKNVLTQLNRVSHDVAVRVAAAIGLGA
PDADDTYYHNNKTAGVSIVGSGPLPTIKTLRVGILATTSESSALDQAAQL
RTRLEKDGLVVTVVAETLREGVDQTYSTADATGFDGVVVVDGAAALFASS
PLFPTGRPLQIFVDAYRWGKPVGVCGEVLDAADVPEDGDGVYSEESVDMF
VEEFEKGLATFRFTDRFALD

3D structure

• PDB: 4b7a Probing the Active Center of Catalase-Phenol Oxidase from Scytalidium Thermophilum
• Chain: D
• Resolution: 1.95 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H82 N155 Q346
• Catalytic site (residue number reindexed from 1): H62 N135 Q326
• Enzyme Commision number: 1.11.1.6: catalase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HDD	D	R79 V81 H82 R119 V153 G154 N155 F160 F168 V228 H229 F345 R365 S368 Y369 T372	R59 V61 H62 R99 V133 G134 N135 F140 F148 V208 H209 F325 R345 S348 Y349 T352
BS02	3TR	D	P158 F226 H246 I313 I314	P138 F206 H226 I293 I294
BS03	3TR	D	L625 F626 P627	L602 F603 P604
BS04	CA	D	R178 H190 D191 S192	R158 H170 D171 S172

Gene Ontology

Molecular Function

• GO:0004096 catalase activity
• GO:0020037 heme binding

Biological Process

• GO:0006979 response to oxidative stress

External links

• PDB: RCSB:4b7a, PDBe:4b7a, PDBj:4b7a
• PDBsum: 4b7a
• UniProt: M4GGR5