Structure of PDB 4awf Chain D

Receptor sequence
>4awfD (length=185) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
MAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMY
SDFHFISIIVENALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLP
DLYDYKENRFIEIGVTRREVHIYYLEKANKIKTHIHIFSFTGEEMATKAD
YTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB4awf Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
ChainD
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D E80 D108 E73 D101
BS02 MN D H41 D108 E119 I120 H43 D101 E112 I113
BS03 XI7 D H41 E80 R84 D108 E119 K134 H43 E73 R77 D101 E112 K127 MOAD: ic50=2.7uM
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4awf, PDBe:4awf, PDBj:4awf
PDBsum4awf
PubMed22876177
UniProtC3W5S0

[Back to BioLiP]