Structure of PDB 4ap9 Chain D

Receptor sequence
>4ap9D (length=200) Species: 342948 (Thermococcus onnurineus) [Search protein sequence]
GAMDPQFMKKVAVIDIEGTLTDFEFWREMARITGKREIEELLEKGLSGEV
EWLDSLLKRVGLIRGIDEGTFLRTREKVNVSPEARELVETLREKGFKVVL
ISGSFEEVLEPFKELGDEFMANRAIFEDGKFQGIRLRFRDKGEFLKRFRD
GFILAMGDGYADAKMFERADMGIAVGREIPGADLLVKDLKELVDFIKNLK
3D structure
PDB4ap9 Identification of a Novel Ligand Binding Site in Phosphoserine Phosphatase from the Hyperthermophilic Archaeon Thermococcus Onnurineus.
ChainD
Resolution1.783 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D8 I9 E10 G96 K134 D155
Catalytic site (residue number reindexed from 1) D15 I16 E17 G103 K141 D162
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1PS D L39 W45 D133 K134 Y153 L46 W52 D140 K141 Y160
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006564 L-serine biosynthetic process
GO:0016311 dephosphorylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4ap9, PDBe:4ap9, PDBj:4ap9
PDBsum4ap9
PubMed23239422
UniProtB6YX36

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