Structure of PDB 3zxt Chain D

Receptor sequence
>3zxtD (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
ENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIVSREDIEREVSI
LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAETEEEATEFLK
QILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDTP
EFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSA
VNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK
3D structure
PDB3zxt A Journey Through the Dap Kinase Architecture
ChainD
Resolution2.65 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161 T180
Catalytic site (residue number reindexed from 1) D118 K120 E122 N123 D140 T149
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP D Q23 A40 I77 E94 V96 M146 I160 D161 Q17 A34 I60 E77 V79 M125 I139 D140
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3zxt, PDBe:3zxt, PDBj:3zxt
PDBsum3zxt
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

[Back to BioLiP]