Structure of PDB 3zq6 Chain D

Receptor sequence
>3zq6D (length=307) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence]
AFKDLFKFNKGKTTFVFIGGKGGVGKTTISAATALWMARSGKKTLVISTD
PAHSLSDSLEREIGHTPTKITENLYAVEIDPEVAMEEYQAKLMLQDQMDM
ASMSPGIDEAAAFDQFLRYMTTDEYDIVIFDTAPTGHTLRLLSFPEIMDS
WVGKMIKIRRQIGSMAKAFKNILPFMGDEEEEDRALQDMEATKKQINAAR
EVMSDPERTSFKMVVIPEEMSIYESERAMKALEKYSIHADGVIVNQVLPE
ESDCEFCNARRKLQQERLKQIREKFSDKVVAEVPLLKKEAKGIETLEKIA
EQLYGEP
3D structure
PDB3zq6 A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein Insertion.
ChainD
Resolution2.107 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G24 G26 K27 T28 T29 D51
Catalytic site (residue number reindexed from 1) G23 G25 K26 T27 T28 D50
Enzyme Commision number 7.3.2.7: arsenite-transporting ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP D K22 E232 M234 K21 E218 M220
BS02 ALF D K22 G23 K21 G22
BS03 ADP D G24 G26 K27 T28 T29 N259 L299 L300 A304 G23 G25 K26 T27 T28 N245 L285 L286 A290
BS04 ALF D G23 G24 K27 D51 G22 G23 K26 D50
BS05 ZN D C268 C271 C254 C257
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015446 ATPase-coupled arsenite transmembrane transporter activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0046685 response to arsenic-containing substance
GO:0071722 detoxification of arsenic-containing substance

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Molecular Function
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Biological Process
External links
PDB RCSB:3zq6, PDBe:3zq6, PDBj:3zq6
PDBsum3zq6
PubMed21658170
UniProtO27555|ARSA_METTH Putative arsenical pump-driving ATPase (Gene Name=MTH_1511)

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