Structure of PDB 3zmk Chain D

Receptor sequence
>3zmkD (length=221) Species: 62324 (Anopheles funestus) [Search protein sequence]
MTKLVLYTLHLSPPCRAVELTAKALGLELEQKNINLLAGDHLTPEFMKLN
PQHTIPVLDDDGTIITESHAIMIYLVTKYGKDDTLYPKDPVQQARVNAAL
HFESGVLFARMRFIFERIFFYGKSDIPEDRVEYVQKSYRLLEDTLKDDFV
AGSKMTIADFSCISTISSIMGVVPLEQSEHPRIYEWIDRLKQLPYYEEAN
GGGGTDLGKFVLAKKEENAKA
3D structure
PDB3zmk A Single Mutation in the Gste2 Gene Allows Tracking of Metabolically-Based Insecticide Resistance in a Major Malaria Vector.
ChainD
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S12
Catalytic site (residue number reindexed from 1) S12
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH D S12 P14 L36 T54 I55 E67 S68 R112 S12 P14 L36 T54 I55 E67 S68 R112
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3zmk, PDBe:3zmk, PDBj:3zmk
PDBsum3zmk
PubMed24565444
UniProtG0XSZ1

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