Structure of PDB 3vq2 Chain D

Receptor sequence
>3vq2D (length=135) Species: 10090 (Mus musculus) [Search protein sequence]
QQWFCNSSDAIISYSYCDHLKFPISISSEPCIRLRGTNGFVHVEFIPRGN
LKYLYFNLFISVNSIELPKRKEVLCHGHDDDYSFCRALKGETVNTSIPFS
FEGILFPKGHYRCVAEAIAGDTEEKLFCLNFTIIH
3D structure
PDB3vq2 Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
ChainD
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LP4 D I52 F65 L74 Y102 F119 S120 I32 F45 L54 Y82 F99 S100
BS02 LP5 D R90 F121 E122 I124 F126 F151 I153 R70 F101 E102 I104 F106 F131 I133
Gene Ontology
Molecular Function
GO:0001530 lipopolysaccharide binding
GO:0035662 Toll-like receptor 4 binding
Biological Process
GO:0045087 innate immune response

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Molecular Function
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Biological Process
External links
PDB RCSB:3vq2, PDBe:3vq2, PDBj:3vq2
PDBsum3vq2
PubMed22532668
UniProtQ9JHF9|LY96_MOUSE Lymphocyte antigen 96 (Gene Name=Ly96)

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