Structure of PDB 3vc1 Chain D

Receptor sequence
>3vc1D (length=288) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]
TTTATATAKIPAPATPYQEDIARYWNNEARPVNLRLGDVDGLYHHHYGIG
PVDRAALGDPEHSEYEKKVIAELHRLESAQAEFLMDHLGQAGPDDTLVDA
GCGRGGSMVMAHRRFGSRVEGVTLSAAQADFGNRRARELRIDDHVRSRVC
NMLDTPFDKGAVTASWNNESTMYVDLHDLFSEHSRFLKVGGRYVTITGCW
NPRYGQPSKWVSQINAHFECNIHSRREYLRAMADNRLVPHTIVDLTPDTL
PYWELRATSSLVTGIEKAFIESYRDGSFQYVLIAADRV
3D structure
PDB3vc1 Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification.
ChainD
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.255: geranyl diphosphate 2-C-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH D Q22 W29 H49 H50 G105 C106 G107 T127 L128 Q132 C154 N155 M156 N172 Y177 Q18 W25 H45 H46 G101 C102 G103 T123 L124 Q128 C150 N151 M152 N168 Y173
BS02 GST D W29 R34 V36 N37 H49 Y51 M176 Y177 F222 R260 W25 R30 V32 N33 H45 Y47 M172 Y173 F218 R256
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008168 methyltransferase activity
GO:0008169 C-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0032259 methylation
GO:0042214 terpene metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3vc1, PDBe:3vc1, PDBj:3vc1
PDBsum3vc1
PubMed22455498
UniProtQ9F1Y5|GPPMT_STRCO Geranyl diphosphate 2-C-methyltransferase (Gene Name=SCO7701)

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