Structure of PDB 3ueo Chain D

Receptor sequence
>3ueoD (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
GLFSQKSFLVLGFSNENESNIANIIKENAGKIMVADYAVVPLLGCEVEAT
VGEVVTNTWLVTCIDYQTLFDPKSNPLFTPVPVMTGMTPLEDCVISFSQC
AGAEKESLTFLANLLGASVQEYFVRKSNAKKGMFASTHLILKERGGSKYE
AAKKWNLPAVTIAWLLETARTGKRADESHFLIENST
3D structure
PDB3ueo Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D S654 Q655 Y678 F679 K687 E699 S703 K704 W711 S98 Q99 Y122 F123 K131 E143 S147 K148 W155
External links
PDB RCSB:3ueo, PDBe:3ueo, PDBj:3ueo
PDBsum3ueo
PubMed23891287
UniProtQ92547|TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (Gene Name=TOPBP1)

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