Structure of PDB 3u5o Chain D

Receptor sequence
>3u5oD (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCR
DIGKPEVEYDCDNLQHSLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI
PNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNE
MMKVVQVYASEVAQAGKAVALYFEDKLTEIYSDRTFA
3D structure
PDB3u5o A poised chromatin platform for TGF-beta access to master regulators
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D D884 N886 D888 W889 Q894 N895 G896 G897 D898 L899 C901 H910 G924 I980 E981 E1061 V1062 D2 N4 D6 W7 Q12 N13 G14 G15 D16 L17 C19 H28 G42 I90 E91 E161 V162
BS02 ZN D C890 C893 H910 C913 C8 C11 H28 C31
BS03 ZN D C902 C905 C931 C20 C23 C49
External links
PDB RCSB:3u5o, PDBe:3u5o, PDBj:3u5o
PDBsum3u5o
PubMed22196728
UniProtQ9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)

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