Structure of PDB 3u1n Chain D

Receptor sequence
>3u1nD (length=424) Species: 9606 (Homo sapiens) [Search protein sequence]
GPGDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFE
HSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFSHM
FDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIC
FIKEQIVGPLLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHL
GIQNNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRA
YQHKVGNIIDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLT
DNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDY
ESLPKEVASAKPKDVKLKAEDFIVDVINMDHVSFYCKEQLIRVYCKKVDR
KSLYAARQYFVQWCADRNFTKPQD
3D structure
PDB3u1n HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
ChainD
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 D D207 H210 H215 D311 D91 H94 H99 D188
BS02 ZN D H167 H206 D207 D311 H51 H90 D91 D188
External links
PDB RCSB:3u1n, PDBe:3u1n, PDBj:3u1n
PDBsum3u1n
PubMed22056990
UniProtQ9Y3Z3|SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Gene Name=SAMHD1)

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