Structure of PDB 3tr5 Chain D

Receptor sequence
>3tr5D (length=508) Species: 777 (Coxiella burnetii) [Search protein sequence]
VEKQTAMRRTFAIISHPDAGKTTLTEKLLLFGGAIQLAGTIKHATSDWME
LEKQRSVTTSVMQFPYKDYLINLLDTPGHADFTEDTYRTLTAVDSALMVI
DAAKGVEPRTIKLMEVCRLRHTPIMTFINKMDRDTRPSIELLDEIESILR
IHCAPVTWPIGMGKYFKGIYHLIEDAIYLYQPGSERIEGINNPELDKKLG
DLASELRNEIELVKGASHPFEREGYLKGELTPIFFGSAINNFGVGELLDA
FVKEAPPPQGRETNSRLVKPEEEKFSGFVFKIQANMDPGHRDRIAFLRIA
SGQYQKGMKAYHVRLKKEIQINNALTFMAGKRENAEEAWPGDIIGLHNHG
TIQIGDTFTQGERFKFTGIPNFASELFRLVRLKDPLKQKALLKGLTQLSE
EGATQLFRPLDSNELILGAVGLLQFDVVAYRLENEYNVKCVYESVNVVTA
RWVICDDKAVLERFNQEQSRNLAYDGGGHLTYLAPSRVNLEITMEKWPEI
QFSETREH
3D structure
PDB3tr5 Structural genomics for drug design against the pathogen Coxiella burnetii.
ChainD
Resolution2.11 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D20
Catalytic site (residue number reindexed from 1) D18
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D Q370 Q414 E417 Q353 Q397 E400
BS02 GDP D D20 G22 K23 T24 T25 H89 N139 K140 D142 S254 I256 D18 G20 K21 T22 T23 H79 N129 K130 D132 S237 I239
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016149 translation release factor activity, codon specific
GO:0016150 translation release factor activity, codon nonspecific
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0006449 regulation of translational termination
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tr5, PDBe:3tr5, PDBj:3tr5
PDBsum3tr5
PubMed26033498
UniProtQ83DC7|RF3_COXBU Peptide chain release factor 3 (Gene Name=prfC)

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