Structure of PDB 3tlx Chain D

Receptor sequence
>3tlxD (length=182) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
ENFSTIDLLNELKRRYACLSKPDGRYIFLGGTQSLNLKKSHCYCHLSTGD
LGLKIKNIINEGKLVDDQMVLSLVPQCKKGFILDGYPRNVKQAEDLNKLL
QKNTKLDGVFYFNVPDEVLVNRISGRLIHKPSGDVLKKRLTVFKSETSPL
ISYYKNKNLLINLDATQPANDLEKKISQHIDG
3D structure
PDB3tlx Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum
ChainD
Resolution2.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R116 R155 R199
Catalytic site (residue number reindexed from 1) R88 R126 R139
Enzyme Commision number 2.7.4.3: adenylate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D G42 T43 P228 A229 G31 T32 P168 A169
Gene Ontology
Molecular Function
GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0019205 nucleobase-containing compound kinase activity
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006139 nucleobase-containing compound metabolic process
GO:0016310 phosphorylation
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3tlx, PDBe:3tlx, PDBj:3tlx
PDBsum3tlx
PubMed
UniProtQ8IJV6|KAD1_PLAF7 Adenylate kinase 1 (Gene Name=AK1)

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