Structure of PDB 3t6q Chain D

Receptor sequence
>3t6qD (length=139) Species: 10090 (Mus musculus) [Search protein sequence]
GWPKHTACNSGGLEVVYQSCDPLQDFGLSIDQCSKQIQSNLNIRFGIILR
QDIRKLFLDITLMAKGSSILNYSYPLCEEDQPKFSFCGRRKGEQIYYAGP
VNNPGLDVPQGEYQLLLELYNENRATVACANATVTSSEF
3D structure
PDB3t6q Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
ChainD
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN D F82 Y145 F57 Y120
BS02 MAN D P100 E103 P75 E78
BS03 MAN D D84 R149 D59 R124
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3t6q, PDBe:3t6q, PDBj:3t6q
PDBsum3t6q
PubMed21959264
UniProtO88188|LY86_MOUSE Lymphocyte antigen 86 (Gene Name=Ly86)

[Back to BioLiP]