Structure of PDB 3sxp Chain D

Receptor sequence
>3sxpD (length=314) Species: 563041 (Helicobacter pylori G27) [Search protein sequence]
MRYIDDELENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNPS
SLGHFKNLIGFKGEVIAADINNPLDLRRLEKLHFDYLFHQAAVSDTTMLN
QELVMKTNYQAFLNLLEIARSKKAKVIYASSAGVYGNTKAPNVVGKNESP
ENVYGFSKLCMDEFVLSHSNDNVQVGLRYFNVYGPREFYKEKTASMVLQL
ALGAMAFKEVKLFEFGEQLRDFVYIEDVIQANVKAMKAQKSGVYNVGYSQ
ARSYNEIVSILKEHLGDFKVTYIKNFFQKHTQAHIEPTILDLDYTPLYDL
ESGIKDYLPHIHAI
3D structure
PDB3sxp The crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase (HP0859) from Helicobacter pylori.
ChainD
Resolution2.55 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S138 A139 G140 Y161 F163 K165 K197
Catalytic site (residue number reindexed from 1) S131 A132 G133 Y154 F156 K158 K190
Enzyme Commision number 5.1.3.20: ADP-glyceromanno-heptose 6-epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D G17 G20 F21 V22 D43 K44 S58 G60 D76 I77 Q97 A98 A99 A136 S138 Y161 K165 Y186 N188 V189 K197 G17 G20 F21 V22 D43 K44 S51 G53 D69 I70 Q90 A91 A92 A129 S131 Y154 K158 Y179 N181 V182 K190
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008712 ADP-glyceromanno-heptose 6-epimerase activity
GO:0016853 isomerase activity
GO:0050661 NADP binding
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3sxp, PDBe:3sxp, PDBj:3sxp
PDBsum3sxp
PubMed21979583
UniProtB5Z7L9

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