Structure of PDB 3se2 Chain D

Receptor sequence
>3se2D (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQA
KKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKG
TYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKN
PQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK
3D structure
PDB3se2 Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AB D H1601 G1602 Y1633 S1641 Y1646 H70 G71 Y102 S110 Y115
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3se2, PDBe:3se2, PDBj:3se2
PDBsum3se2
PubMed22343925
UniProtQ460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 (Gene Name=PARP14)

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