Structure of PDB 3rnu Chain D

Receptor sequence
>3rnuD (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]
SAQSDLKEVMVLNATESFVYEPKEQKKMFHATVATENEVFRVKVFNIDLK
EKFTPKKIIAIANYVCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASV
TPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGR
LTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNAAAS
3D structure
PDB3rnu Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.
ChainD
Resolution2.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R667 R764 R96 R193
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:3rnu, PDBe:3rnu, PDBj:3rnu
PDBsum3rnu
PubMed22483801
UniProtQ16666|IF16_HUMAN Gamma-interferon-inducible protein 16 (Gene Name=IFI16)

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