Structure of PDB 3ri4 Chain D

Receptor sequence
>3ri4D (length=136) Species: 9606 (Homo sapiens) [Search protein sequence]
GTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQ
SFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNI
IHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKP
3D structure
PDB3ri4 Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Q336 L337 W375 K379 M384 K388 R391 Y395 Y396 K399 Q35 L36 W74 K78 M83 K87 R90 Y94 Y95 K98
BS02 dna D P334 Y386 R391 R394 Y395 Y397 K404 R409 Y410 P33 Y85 R90 R93 Y94 Y96 K103 R108 Y109
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:3ri4, PDBe:3ri4, PDBj:3ri4
PDBsum3ri4
PubMed22432043
UniProtP14921|ETS1_HUMAN Protein C-ets-1 (Gene Name=ETS1)

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