Structure of PDB 3rae Chain D

Receptor sequence
>3raeD (length=209) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
KLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVINTAK
AKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDADTDGAHI
QTLLLTFFYRYMRPLVEAGHVYIALPPLYKMYAWTDGELEELRKQLQRYK
GLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGDKVEPRRK
WIEDNVKFT
3D structure
PDB3rae Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex.
ChainD
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D D435 S436 D21 S22
BS02 dna D G457 K458 D510 G43 K44 D96
BS03 dna D K458 I460 N461 K464 H513 V626 R629 K44 I46 N47 K50 H99 V195 R198
BS04 MG D D506 D508 D92 D94
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:3rae, PDBe:3rae, PDBj:3rae
PDBsum3rae
PubMed27050128
UniProtQ59961|PARE_STRPN DNA topoisomerase 4 subunit B (Gene Name=parE)

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