Structure of PDB 3qxd Chain D

Receptor sequence
>3qxdD (length=178) Species: 9606 (Homo sapiens) [Search protein sequence]
EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFAS
CEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPN
VLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPF
LPSTEDVYDCRVEHWGLDEPLLKHWEFD
3D structure
PDB3qxd Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange.
ChainD
Resolution2.302 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Q9 F24 F51 A52 S53 C54 G58 A59 N62 N69 I72 M73 Q6 F21 F48 A49 S50 C51 G55 A56 N59 N66 I69 M70
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:3qxd, PDBe:3qxd, PDBj:3qxd
PDBsum3qxd
PubMed22084083
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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