Structure of PDB 3pgj Chain D

Receptor sequence
>3pgjD (length=271) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
IDQYAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHF
FAQGGRGCNVTVPFKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDN
TDGEGLVQDLLAQQVLLKGATILLIGAGGAARGVLKPLLDQQPASITVTN
RTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAID
PVIFSSRSVCYDMMYGKGYTVFNQWARQHGCAQAIDGLGMLVGQAAESFM
LWRGLRPGTKQILRELRKNLE
3D structure
PDB3pgj 2.49 Angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroE) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with shikimate
ChainD
Resolution2.49 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SKM D S18 S20 T65 K69 D106 Q248 S14 S16 T61 K65 D102 Q244
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0008150 biological_process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3pgj, PDBe:3pgj, PDBj:3pgj
PDBsum3pgj
PubMed
UniProtQ9KVT3|AROE_VIBCH Shikimate dehydrogenase (NADP(+)) (Gene Name=aroE)

[Back to BioLiP]