Structure of PDB 3or2 Chain D

Receptor sequence

>3or2D (length=435) Species: 879 (Megalodesulfovibrio gigas)

KHPTPMLDELEKGPWPSFVSDIKQECDNRAKNPKGLDYQIPAECPDDLLG
ILELSFHEGETHWKHGGIVGVFGYGGGVIGRYCDQPEMFPGVAHFHTVRL
AQPAAKYYTAEYLEAICDVWDLRGSGLTNMHGSTGDIVLLGTQTPQLEEI
FFEMTHNLNTDLGGSGSNLRTPESCLGISRCEFACYDTQLMCYQLTQDYQ
DELHRPAFPYKFKFKFDGCPNGCVASMARSDFAVIGTWKDDIKIDQEAVK
AYVGGEFKPNAGAHAGRDWGKFDIEAEVVGLCPTGCMTYESGTLSIDNKN
CTRCMHCINTMPRALKIGDERGASILVGAKAPVLDGAQMGSLLIPFIAAE
EPFDEVKEVIENIWEWWMEEGKNRERLGETMKRVGFQKLLEVTGTKAVPQ
HVSEPRHNPYIFFKEEEVPGGWSRDISDYRKRHMR

3D structure

• PDB: 3or2 Dissimilatory Sulfite Reductase, Sulfate Reduction
• Chain: D
• Resolution: 2.05 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SF4	D	C284 P285 C288 M289 C303 T304 R305 C306 M307 C309	C282 P283 C286 M287 C301 T302 R303 C304 M305 C307
BS02	SF4	D	C177 L178 C183 F185 A186 G220 C221 N223 C225	C175 L176 C181 F183 A184 G218 C219 N221 C223
BS03	SO3	D	H67 G69	H65 G67
BS04	SRM	D	R83 R101 G134 S135 T136 D138 Y212 K213 K215 K217 R231 K332 A333 V335 R378	R81 R99 G132 S133 T134 D136 Y210 K211 K213 K215 R229 K330 A331 V333 R376
BS05	SO3	D	R172 K213 K215	R170 K211 K213
BS06	SRM	D	C177 L178 C183 E184 N223 G224 C225 N262 N311	C175 L176 C181 E182 N221 G222 C223 N260 N309

Gene Ontology

Molecular Function

• GO:0016002 sulfite reductase activity
• GO:0016491 oxidoreductase activity
• GO:0018551 dissimilatory sulfite reductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0050311 sulfite reductase (ferredoxin) activity
• GO:0051536 iron-sulfur cluster binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0000103 sulfate assimilation

Cellular Component

• GO:0009337 sulfite reductase complex (NADPH)

External links

• PDB: RCSB:3or2, PDBe:3or2, PDBj:3or2
• PDBsum: 3or2
• UniProt: E2QR97