Structure of PDB 3ofn Chain D

Receptor sequence
>3ofnD (length=470) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
STPITGKVTAVIGAIVDVHFEQSELPAILNALEIKTPQGKLVLEVAQHLG
ENTVRTIAMDGTEGLVRGEKVLDTGGPISVPVGRETLGRIINVIGEPIDE
RGPIKSKLRKPIHADPPSFAEQSTSAEILETGIKVVDLLAPYARGGKIGL
FGGAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETG
VINLEGESKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFI
DNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTKKGSVT
SVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKS
RLLDAAVVGQEHYDVASKVQETLQTYKSLQDIIAILGMDELSEQDKLTVE
RARKIQRFLSQPFAVAEVFTGIPGKLVRLKDTVASFKAVLEGKYDNIPEH
AFYMVGGIEDVVAKAEKLAA
3D structure
PDB3ofn Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling.
ChainD
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K163 E189 R190 R356
Catalytic site (residue number reindexed from 1) K158 E184 R185 R351
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP D G160 G162 K163 T164 V165 R190 Y345 A421 F424 G155 G157 K158 T159 V160 R185 Y340 A416 F419
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0016020 membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0045267 proton-transporting ATP synthase, catalytic core

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ofn, PDBe:3ofn, PDBj:3ofn
PDBsum3ofn
PubMed20843806
UniProtP00830|ATPB_YEAST ATP synthase subunit beta, mitochondrial (Gene Name=ATP2)

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