Structure of PDB 3n7s Chain D

Receptor sequence
>3n7sD (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
CQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHM
AEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRA
3D structure
PDB3n7s Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3N6 D A70 D71 W74 W84 A44 D45 W48 W58 PDBbind-CN: -logKd/Ki=7.70,Kd=20nM
Gene Ontology
Molecular Function
GO:0015026 coreceptor activity
Biological Process
GO:0006886 intracellular protein transport
GO:0008277 regulation of G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3n7s, PDBe:3n7s, PDBj:3n7s
PDBsum3n7s
PubMed20826335
UniProtO60894|RAMP1_HUMAN Receptor activity-modifying protein 1 (Gene Name=RAMP1)

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