Structure of PDB 3ml4 Chain D

Receptor sequence
>3ml4D (length=206) Species: 10090 (Mus musculus) [Search protein sequence]
EAALVEGQVKLRDKWKSRWLVLRKPSPVADCLLMLVYKDKCERSKGLRER
SSLTLEDICGLEPALPYEGLAHTLAIICLSQAVMLGFDSHEAMCAWDTRI
RYALGEVHRFHVTVAPGTKLESGPATLHLCNDILVLARDIPPTVMGQWKL
SDLRRYGAVPNGFIFEGGTRCGYWAGVFFLSSAEGEQMSFLFDCIVRGIS
PTKGPF
3D structure
PDB3ml4 The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D E3 L39 E53 E1 L35 E49
BS02 peptide D S155 D156 L157 R158 Y160 G161 G172 T173 R174 V200 S151 D152 L153 R154 Y156 G157 G168 T169 R170 V196
Gene Ontology
Molecular Function
GO:0019901 protein kinase binding
Biological Process
GO:0061098 positive regulation of protein tyrosine kinase activity

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Molecular Function
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Biological Process
External links
PDB RCSB:3ml4, PDBe:3ml4, PDBj:3ml4
PDBsum3ml4
PubMed20603078
UniProtQ18PE0|DOK7_MOUSE Protein Dok-7 (Gene Name=Dok7)

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