Structure of PDB 3m81 Chain D

Receptor sequence
>3m81D (length=322) Species: 2336 (Thermotoga maritima) [Search protein sequence]
FFDLPLEELKKYRPERYEEKDFDEFWEETLAESEKFPLDPVFERMESHLK
TVEAYDVTFSGYRGQRIKGWLLVPKLEEEKLPCVVQYIGYNGGRGFPHDW
LFWPSMGYICFVMDTRGQGSGWLKGDTPDYPEGPVDPQYPGFMTRGILDP
RTYYYRRVFTDAVRAVEAAASFPQVDQERIVIAGGSQGGGIALAVSALSK
KAKALLCDVPFLCHFRRAVQLVDTHPYAEITNFLKTHRDKEEIVFRTLSY
FDGVNFAARAKIPALFSVGLMDNICPPSTVFAAYNYYAGPKEIRIYPYNN
HEGGGSFQAVEQVKFLKKLFEK
3D structure
PDB3m81 Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
ChainD
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S188 Q189 D274 H303
Catalytic site (residue number reindexed from 1) S186 Q187 D272 H301
Enzyme Commision number 3.1.1.41: cephalosporin-C deacetylase.
3.1.1.72: acetylxylan esterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D E45 D58 E43 D56
BS02 ACT D Q140 G143 R147 Q138 G141 R145
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046555 acetylxylan esterase activity
GO:0046872 metal ion binding
GO:0047739 cephalosporin-C deacetylase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0005976 polysaccharide metabolic process
GO:0030245 cellulose catabolic process
GO:0045491 xylan metabolic process
GO:1901266 cephalosporin C metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3m81, PDBe:3m81, PDBj:3m81
PDBsum3m81
PubMed22411095
UniProtQ9WXT2|CAH_THEMA Cephalosporin-C deacetylase (Gene Name=axeA)

[Back to BioLiP]