Structure of PDB 3laj Chain D

Receptor sequence
>3lajD (length=155) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
ANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGA
VKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLA
VLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGM
FENLR
3D structure
PDB3laj crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
ChainD
Resolution2.306 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D S36 Q37 Q53 A54 S57 R58 K67 Y78 S21 Q22 Q38 A39 S42 R43 K52 Y63
BS02 dna D R18 R21 V51 T52 T55 R58 T75 R3 R6 V36 T37 T40 R43 T60
BS03 ARG D S129 D132 T142 S114 D117 T127
BS04 ARG D G145 D146 G130 D131
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0034618 arginine binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0051259 protein complex oligomerization
GO:1900079 regulation of arginine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3laj, PDBe:3laj, PDBj:3laj
PDBsum3laj
PubMed20382162
UniProtP9WPY9|ARGR_MYCTU Arginine repressor (Gene Name=argR)

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