Structure of PDB 3l25 Chain D

Receptor sequence
>3l25D (length=123) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB3l25 Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
ChainD
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D G234 A306 K309 G17 A89 K92 PDBbind-CN: Kd=500nM
BS02 rna D F239 S272 Q274 C275 I340 F22 S55 Q57 C58 I123 PDBbind-CN: Kd=500nM
External links
PDB RCSB:3l25, PDBe:3l25, PDBj:3l25
PDBsum3l25
PubMed20081868
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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