Structure of PDB 3kt6 Chain D

Receptor sequence
>3kt6D (length=409) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
LKSTDVKEQVVTPWDVEGGVDEQGRAQNIDYDKLIKQFGTKPVNEETLKR
FKQVTGREPHHFLRKGLFFSERDFTKILDLYEQGKPFFLYTGRGPSSDSM
HLGHMIPFVFTKWLQEVFDVPLVIELTDDEKFLFKHKLTINDVKNFAREN
AKDIIAVGFDPKNTFIFSDLQYMGGAFYETVVRVSRQITGSTAKAVFGFN
DSDCIGKFHFASIQIATAFPSSFPNVLGLPDKTPCLIPCAIDQDPYFRVC
RDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQK
KINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVFLKECYDKY
KSGELLSGEMKKLCIETLQEFVKAFQERRAQVDEETLDKFMVPHKLVWGE
KERLVAPKP
3D structure
PDB3kt6 Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.2: tryptophan--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TRP D Y106 T107 G108 R109 E141 E146 Q230 C255 Q259 F263 Y90 T91 G92 R93 E125 E130 Q214 C239 Q243 F247
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004830 tryptophan-tRNA ligase activity
GO:0005524 ATP binding
GO:1990825 sequence-specific mRNA binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006436 tryptophanyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:3kt6, PDBe:3kt6, PDBj:3kt6
PDBsum3kt6
PubMed20123733
UniProtQ12109|SYWC_YEAST Tryptophan--tRNA ligase, cytoplasmic (Gene Name=WRS1)

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