Structure of PDB 3it6 Chain D

Receptor sequence
>3it6D (length=205) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTNDTVLLLSSG
ASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDA
LVAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGA
AVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEEN
SAYSS
3D structure
PDB3it6 The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.
ChainD
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.1: amino-acid N-acetyltransferase.
2.3.1.35: glutamate N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ORN D T200 E280 N399 S404 T1 E81 N200 S205
Gene Ontology
Molecular Function
GO:0004358 glutamate N-acetyltransferase activity
Biological Process
GO:0006526 L-arginine biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3it6, PDBe:3it6, PDBj:3it6
PDBsum3it6
PubMed20184895
UniProtP9WPZ3|ARGJ_MYCTU Arginine biosynthesis bifunctional protein ArgJ (Gene Name=argJ)

[Back to BioLiP]